Centre to Set Up Region’s 1st Arab Genome project

DUBAI — A UAE research centre is set to embark on the first Arab Genome Project in the region that will map genes in the Arab population and provide a platform for future medical practice.

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Asma Ali Zain

Published: Mon 15 Mar 2010, 12:28 AM

Last updated: Mon 6 Apr 2015, 3:20 PM

The project will study the difference between people, which will also explain the spread of specific illnesses such as diabetes, heart diseases and cancers, said Dr Mahmoud Taleb Al Ali, Director of the Centre for Arab Genomic Studies (CAGS), during the opening of the third Pan-Arab Human Genetic Conference in Dubai on Saturday. The UAE Minister of Health, Dr Hanif Hassan inaugurated the two-day conference in Al Bustan Rotana Hotel.

He was talking about the future plans of the centre that will now also extend the Catalogue for Transmission Genetics in Arabs (CTGA) database to include the entire spectrum of genetic disorders in the Arab world.

Scientists at the centre have already conducted extensive clinical and molecular analysis for families which is expected to bring fresh insights to the human genome with particular reference to the Arab population, he said.

“The project will study genetic variability in the Arab world to screen for natural difference between humans,” explained Dr Ghazi Omar Tadmouri, Assistant Director for CAGS.

The first phase of the Emirates Family Registry (EFR) to screen for Type-2 diabetes in indigenous population, that was launched in 2007, is also nearing its end, said Dr Kamal Khazanehdari, Molecular Geneticist at the Central Veterinary Research Laboratory.

He was speaking on behalf of Emirati national Habiba Al Safar who is spearheading the project among the Bedouin population and is currently completing her PhD degree abroad.

DNA samples from 1,766 Bedouin donors with type 2 diabetes were collected. “Understanding the environmental factors and genetic predisposition were important aims of this study to ensure successful implementation of future public awareness programmes,” said the geneticist.

“The project will be expanded to include disorders such as obesity, mental health and Down’s Syndrome for study purposes,” he said, adding that the project will also include indigenous other populations including Persians, Kurds, Lebanese, Palestinians, Turks and others.

“Results from the research are aimed at providing improved intervention and prevention programmes to improve the quality of life throughout the Arab world,” said Dr Khazanehdari.

The project has recruited volunteers from three local hospitals and nine primary healthcare centres. Through this network, 23,064 volunteers provided consent to allow their clinical data to be stored in the EFR database.

asmaalizain@khaleejtimes.com

Asma Ali Zain

Published: Mon 15 Mar 2010, 12:28 AM

Last updated: Mon 6 Apr 2015, 3:20 PM

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