Why some Covid recovered people are at risk of blood clots

Singapore - Overactive immune response responsible for condition, researchers say.

People who have recovered from Covid-19, especially those with pre-existing cardiovascular conditions, may be at risk of developing blood clots due to a lingering and overactive immune response, according to a study.

The study, led by researchers from the Nanyang Technological University in Singapore, found that recovered Covid-19 patients had twice the normal number of circulating endothelial cells (CECs) that had been shed from damaged blood vessel walls.

The elevated levels of CECs indicate that blood vessel injury is still apparent after recovering from viral infection.

The recovered Covid-19 patients also continued to produce high levels of cytokines -- proteins produced by immune cells that activate the immune response against pathogens -- even in the absence of the virus.

Unusually high numbers of immune cells, known as T cells, that attack and destroy viruses were also present in the blood of recovered Covid-19 patients.

The presence of both cytokines and higher levels of immune cells suggest that the immune systems of recovered Covid-19 patients remained activated even once the virus was gone, revealed the findings published in the peer-reviewed scientific journal eLife.