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On Thursday, the EU's drug regulator is expected to authorise the first Covid-19 vaccines for the Omicron variant, although they do not target the latest strains.
The adapted vaccines made by Pfizer/BioNTech and Moderna will be discussed during an extraordinary meeting of the European Medicines Agency (EMA).
European nations have been keen to rush through the new generation of jabs so they can start booster campaigns, ahead of a feared Covid surge this winter.
The two so-called "bivalent" vaccines protect against the earlier BA.1 strain of Omicron, as well as the original Covid-19 virus that emerged in China in 2019.
They do not, however, target the newer and more infectious BA.4 and BA.5 types, which have emerged in recent months as the dominant strains worldwide.
"The aim of the meeting is to conclude the evaluation of the two applications, if possible," the Amsterdam-based EMA said.
"We will communicate on the outcomes of the meeting on 1 September."
The agency has said it hopes to approve a separate Pfizer vaccine adapted for the BA.4 and BA.5 types "in the fall".
The United States authorised its first anti-Omicron vaccines on Wednesday, approving Pfizer and Moderna jabs that were adapted to tackle BA.4 and BA.5.
Britain authorised the Moderna vaccine for the BA.1 type in mid-August.
The 27-nation EU is currently (still) using the same coronavirus vaccines that were approved nearly two years ago for use against the original strain.
While they offer some protection against newer variants, the race has been on to produce jabs that also target the milder (but more infectious) Omicron strains.
While previous "variants of concern" like Alpha and Delta eventually petered out, Omicron and its sub lineages have dominated throughout 2022. The BA.4 and BA.5 types have, in particular, helped to drive a wave of new cases of the disease in Europe and the the United States in recent months. Health authorities have therefore been keen to get updated vaccines as soon as possible, ahead of a feared new wave of the disease later this year.
All Omicron variants tend to have a milder disease course — they settle less in the lungs and more in the upper nasal passages, causing symptoms like fever, tiredness and loss of smell.
The EMA said its review of the adapted Pfizer and Moderna vaccines focused on data from laboratory studies as well as tests on the immune response against the original strain and the Omicron variant.
The adapted vaccines under consideration on Thursday "more closely match the original strain and the BA.1 Omicron subvariant", the agency said.
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