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Obama is in San Francisco, where he is set to meet with tech industry leaders on Friday.
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There is a very real risk that Scotland at least could leave the United Kingdom. This would substantially aggravate political and economic instability Howard Archer, chief UK and European economist at IHS Global Insight
Foreign ministers from the EU's six founding countries - France, Germany, Italy, Belgium, the Netherlands and Luxembourg - are expected to meet on Saturday in Berlin.
Britain has voted to leave the European Union to take greater control of its economy and its borders, shattering the stability of the continental unity forged after World War II. The decision launches what will be years of negotiations over trade, business and political links with the EU, which will shrink to a 27-nation bloc.
US futures took a dive. Dow futures fell 3.9 percent and S&P futures nosedived 5.1 percent.
Official results released early Friday show the "leave" side prevailed 52 per cent to 48 percent in Thursday's vote.
The EU is in shock and entering uncharted territory. No member state has ever left and Article 50 of the EU treaty, which sets out how a state can exit the bloc, offers little detail.
A vote to leave the EU would destabilize the 28-nation trading bloc, created from the ashes of World War II to keep the peace in Europe.
Voters in Gibraltar were massively in favour of staying in the EU and the Orkney Islands also ended up in the Remain column.